Developmental programming and endocrine disruptor effects on reproductive neuroendocrine systems
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چکیده
منابع مشابه
Effects of an Endocrine Disruptor on Male Reproductive Organs
A 5-day Hershberger assay, a 20-day pubertal male assay, a one-month oral administration study and a reproductive toxicity study were carried out using an antiandrogenic chemical, flutamide (FL). The effects of FL were as follows: weight decrease in male reproductive organs such as the prostate and seminal vesicles were observed at ≥0.6 mg/kg/day as the most sensitive parameter in the Hershberg...
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In 1996, the US Congress mandated that the US Environmental Protection Agency (EPA) create and regulate the Endocrine Disruptor Screening Program. The program tests industrial and agricultural chemicals for hormonal impacts in humans [3] and in wildlife that may disrupt organisms' endocrine systems. The endocrine system regulates the release of small amounts of chemical substances called hormon...
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ژورنال
عنوان ژورنال: Frontiers in Neuroendocrinology
سال: 2008
ISSN: 0091-3022
DOI: 10.1016/j.yfrne.2008.02.002